Francesco Impagnatiello Selected Research

1-(aminomethyl)cyclohexaneacetic acid 3-(nitrooxymethyl)phenyl ester

1/2004

A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.

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Francesco Impagnatiello Research Topics

Disease

7	Ocular Hypertension (Glaucoma, Suspect) 01/2021 - 04/2010
7	Glaucoma 01/2021 - 04/2010
4	Inflammation (Inflammations) 01/2013 - 06/2004
4	Parkinson Disease (Parkinson's Disease) 01/2013 - 02/2002
2	Reperfusion Injury 01/2022 - 05/2012
2	Hyperalgesia 05/2016 - 01/2004
2	Neuralgia (Stump Neuralgia) 09/2009 - 01/2004
2	Pain (Aches) 09/2009 - 01/2004
1	Ischemia 01/2022
1	Diabetic Neuropathies (Diabetic Neuropathy) 05/2016
1	Gliosis 01/2013
1	Nervous System Diseases (Neurological Disorders) 01/2013
1	Diabetic Retinopathy (Retinopathy, Diabetic) 05/2012
1	Necrosis 05/2012
1	Eye Diseases (Eye Disease) 04/2011
1	Neuroinflammatory Diseases 11/2010
1	Cardiotoxicity 11/2010
1	Open-Angle Glaucoma (Glaucoma, Open Angle) 12/2009
1	Dyskinesias (Dyskinesia) 07/2009
1	Mental Disorders (Mental Disorder) 07/2009
1	Movement Disorders (Movement Disorder) 07/2009
1	Pulmonary Embolism 09/2007
1	Encephalitis (Encephalitis, Rasmussen) 02/2006
1	Atherosclerotic Plaque (Atheroma) 06/2004
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2004
1	Peripheral Nerve Injuries 01/2004

Drug/Important Bio-Agent (IBA)

11	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 01/2004
2	Retinaldehyde (Retinal)IBA 01/2022 - 05/2012
2	Bimatoprost (Lumigan)FDA Link 01/2019 - 10/2015
2	Synthetic Prostaglandins (Prostaglandin Analogues)IBA 01/2019 - 04/2010
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2013 - 11/2010
2	AntioxidantsIBA 09/2009 - 02/2006
2	3- ((4- hydroxy- 3- methoxyphenyl)- 2- propenoic acid 4-nitrooxy)butyl esterIBA 09/2009 - 02/2006
2	Levodopa (L Dopa)FDA LinkGeneric 07/2009 - 02/2002
2	Pharmaceutical PreparationsIBA 02/2006 - 01/2004
1	Endothelin-1 (Endothelin 1)IBA 01/2022
1	avanafilIBA 01/2021
1	1,4-3,6-dianhydromannitolIBA 01/2021
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2021
1	1,2,5-oxadiazole 2-oxideIBA 01/2017
1	Pregabalin (Lyrica)FDA Link 05/2016
1	Streptozocin (Streptozotocin)FDA Link 05/2016
1	hexanoic acid (hexanoate)IBA 05/2016
1	5- methyl- 3- (((1- (4- (nitrooxy)butanoyloxy)ethoxy)carbonylamino)methyl)hexanoic acidIBA 05/2016
1	Interleukin-6 (Interleukin 6)IBA 05/2012
1	3-nitrotyrosineIBA 05/2012
1	NCX 434IBA 05/2012
1	SulfonamidesIBA 02/2012
1	carbomerIBA 02/2012
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 02/2012
1	isosorbide-5-mononitrate (Ismo)FDA LinkGeneric 02/2012
1	dorzolamide (Trusopt)FDA LinkGeneric 02/2012
1	NCX250IBA 02/2012
1	BOL 303259-XIBA 09/2011
1	GlucocorticoidsIBA 04/2011
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 11/2010
1	Latanoprost (Xalatan)FDA Link 04/2010
1	1-(nitrooxymethyl)-2-(nitrooxy)ethyl 7- (3,5- dihydroxy- 2- (3- hydroxy- 5- phenylpentyl)cyclopentyl)- 5- heptenoateIBA 04/2010
1	Carbonic Anhydrase InhibitorsIBA 12/2009
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2009
1	CarrageenanIBA 09/2009
1	AminesIBA 07/2009
1	2- (2- furanyl)- 7- (2- (4- (4- (2- methoxyethoxy)phenyl)- 1- piperazinyl)ethyl)- 7H- pyrazolo(4,3- e)(1,2,4)triazolo(1,5- c)pyrimidine- 5- amineIBA 07/2009
1	(7- (2- (4- difluorophenyl)- 1- piperazinyl)ethyl)- 2- (2- furanyl)- 7H- pyrazolo(4,3- e)(1,2,4)triazolo(1,5- c)pyrimidin- 5- amineIBA 07/2009
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 07/2009
1	NCX 6560IBA 09/2007
1	CollagenIBA 09/2007
1	Epinephrine (Adrenaline)FDA LinkGeneric 09/2007
1	ferulic acid (sodium ferulate)IBA 02/2006
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 06/2004
1	EnzymesIBA 01/2004
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2004
1	CyclohexaneIBA 01/2004
1	1-(aminomethyl)cyclohexaneacetic acid 3-(nitrooxymethyl)phenyl esterIBA 01/2004
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2004
1	EstersIBA 01/2004
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2004

Therapy/Procedure

4	Lasers (Laser) 01/2021 - 04/2010
2	Therapeutics 11/2010 - 06/2004